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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK1
All Species:
40.91
Human Site:
S266
Identified Species:
69.23
UniProt:
P28482
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28482
NP_002736.3
360
41390
S266
K
A
R
N
Y
L
L
S
L
P
H
K
N
K
V
Chimpanzee
Pan troglodytes
XP_510921
379
43006
S283
K
A
R
N
Y
L
Q
S
L
P
S
K
T
K
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860750
375
42862
S266
K
A
R
N
Y
L
L
S
L
P
H
K
N
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
S284
K
A
R
N
Y
L
Q
S
L
P
S
K
T
K
V
Rat
Rattus norvegicus
P63086
358
41257
S264
K
A
R
N
Y
L
L
S
L
P
H
K
N
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
S274
K
A
R
N
Y
L
L
S
L
P
H
K
N
K
V
Frog
Xenopus laevis
P26696
361
41238
S269
K
A
R
N
Y
L
L
S
L
P
H
K
N
K
V
Zebra Danio
Brachydanio rerio
NP_878308
369
42057
S275
K
A
R
N
Y
L
L
S
L
P
L
R
S
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
S329
K
A
R
N
Y
L
E
S
L
P
F
K
P
N
V
Honey Bee
Apis mellifera
XP_393029
371
42705
S268
K
A
R
N
Y
L
Q
S
L
P
Y
K
P
K
V
Nematode Worm
Caenorhab. elegans
P39745
444
50644
S337
K
A
R
S
Y
L
I
S
L
P
H
K
P
K
Q
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
G272
K
A
R
A
Y
L
Q
G
L
P
F
K
S
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
Q282
N
A
R
R
Y
V
R
Q
L
P
Q
Y
P
R
Q
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
K261
P
R
A
R
E
Y
I
K
S
L
P
M
Y
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
N.A.
96
N.A.
83.4
99.1
N.A.
N.A.
97.2
95.8
92.1
N.A.
67.8
81.9
64.4
79.4
Protein Similarity:
100
85.4
N.A.
96
N.A.
89.2
99.4
N.A.
N.A.
97.5
97.2
94.5
N.A.
74.6
86.7
70.9
84.5
P-Site Identity:
100
80
N.A.
100
N.A.
80
100
N.A.
N.A.
100
100
80
N.A.
73.3
80
73.3
60
P-Site Similarity:
100
80
N.A.
100
N.A.
80
100
N.A.
N.A.
100
100
93.3
N.A.
73.3
86.6
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.4
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
93
8
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
8
% I
% Lys:
86
0
0
0
0
0
0
8
0
0
0
79
0
79
0
% K
% Leu:
0
0
0
0
0
86
43
0
93
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
72
0
0
0
0
0
0
0
0
36
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
93
8
0
29
8
0
% P
% Gln:
0
0
0
0
0
0
29
8
0
0
8
0
0
0
15
% Q
% Arg:
0
8
93
15
0
0
8
0
0
0
0
8
0
8
0
% R
% Ser:
0
0
0
8
0
0
0
79
8
0
15
0
15
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
72
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
93
8
0
0
0
0
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _